بررسی اثرات سمیت سلولی و آپاپتوز سیلیمارین بر روی رده سلولی سرطان کولون (SW480)

Bayram, D., Çetin, E.S., Kara, M., Özgöçmen, M. and Candan, I. 2017. The apoptotic effects of silibinin on mda-mb-231 and mcf-7 human breast carcinoma cells. Human & experimental toxicology, 36(6): 573-586.

Chirumbolo, S., Bjørklund, G., Lysiuk, R., Vella, A., Lenchyk, L. and Upyr, T. 2018. Targeting cancer with phytochemicals via their fine tuning of the cell survival signaling pathways. International journal of molecular sciences, 19(11): 3568.

Choi, E.-S., Oh, S., Jang, B., Yu, H.-J., Shin, J.-A., Cho, N.-P., Yang, I.-H., Won, D.-H., Kwon, H.-J. and Hong, S.D. 2017. Silymarin and its active component silibinin act as novel therapeutic alternatives for salivary gland cancer by targeting the erk1/2-bim signaling cascade. Cellular Oncology, 40(3): 235-246.

de Avelar, C.R., Pereira, E.M., de Farias Costa, P.R., de Jesus, R.P. and de Oliveira, L.P.M. 2017. Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis. World journal of gastroenterology, 23(27): 5004.

Deep, G., Singh, R., Agarwal, C., Kroll, D. and Agarwal, R. 2006. Silymarin and silibinin cause g1 and g2–m cell cycle arrest via distinct circuitries in human prostate cancer pc3 cells: A comparison of flavanone silibinin with flavanolignan mixture silymarin. Oncogene, 25(7): 1053-1069.

Delmas, D., Xiao, J., Vejux, A. and Aires, V. 2020. Silymarin and cancer: A dual strategy in both in chemoprevention and chemosensitivity. Molecules, 25(9): 2009.

Farag, R.S., Abdel-Latif, M.S., Abd El Baky, H.H. and Tawfeek, L.S. 2020. Phytochemical screening and antioxidant activity of some medicinal plants’ crude juices. Biotechnology Reports, 28: e00536.

Federico, A., Dallio, M. and Loguercio, C. 2017. Silymarin/silybin and chronic liver disease: A marriage of many years. Molecules, 22(2): 191.

Gheybi, F., Alavizadeh, S.H., Rezayat, S.M., Zendedel, E. and Jaafari, M. 2019. Chemotherapeutic activity of silymarin combined with doxorubicin liposomes in 4t1 breast cancer cells. Nanomedicine Research Journal, 4(1): 29-34.

Girardi, B., Principi, M., Pricci, M., Giorgio, F., Iannone, A., Losurdo, G., Ierardi, E., Di Leo, A. and Barone, M. 2018. Chemoprevention of inflammation-related colorectal cancer by silymarin-, acetyl-11-keto-beta-boswellic acid-, curcumin-and maltodextrin-enriched dietetic formulation in animal model. Carcinogenesis, 39(10): 1274-1282.

Hagag, A.A., Elgamsy, M.A., El-Asy, H.M. and Mabrouk, M.M. 2016. Protective role of silymarin on hepatic and renal toxicity induced by mtx based chemotherapy in children with acute lymphoblastic leukemia. Mediterranean journal of hematology and infectious diseases, 8(1).

Hekmat, A., Salavati, F. and Tackallou, S.H. 2020. The effects of paclitaxel in the combination of diamond nanoparticles on the structure of human serum albumin (hsa) and their antiproliferative role on mda-mb-231cells. The Protein Journal: 1-16.

Iqbal, B., Ali, J., Ganguli, M., Mishra, S. and Baboota, S. 2019. Silymarin-loaded nanostructured lipid carrier gel for the treatment of skin cancer. Nanomedicine, 14(9): 1077-1093.

Kim, S.H., Choo, G.S., Yoo, E.S., Woo, J.S., Han, S.H., Lee, J.H. and Jung, J.Y. 2019. Silymarin induces inhibition of growth and apoptosis through modulation of the mapk signaling pathway in ags human gastric cancer cells. Oncology reports, 42(5): 1904-1914.

Mehta, A. and Patel, B.M. 2019. Therapeutic opportunities in colon cancer: Focus on phosphodiesterase inhibitors. Life sciences, 230: 150-161.

Pashah, Z., Hekmat, A. and Hesami Tackallou, S. 2019. Structural effects of diamond nanoparticles and paclitaxel combination on calf thymus DNA. Nucleosides, Nucleotides and Nucleic Acids, 38(4): 249-278.

Shi, Z., Zhou, Q., Gao, S., Li, W., Li, X., Liu, Z., Jin, P. and Jiang, J. 2019. Silibinin inhibits endometrial carcinoma via blocking pathways of stat3 activation and srebp1-mediated lipid accumulation. Life sciences, 217: 70-80.

Siegel, R.L., Miller, K.D., Goding Sauer, A., Fedewa, S.A., Butterly, L.F., Anderson, J.C., Cercek, A., Smith, R.A. and Jemal, A. 2020. Colorectal cancer statistics, 2020. CA: a cancer journal for clinicians, 70(3): 145-164.

Soodvilai, S., Tipparos, W., Rangsimawong, W., Patrojanasophon, P., Soodvilai, S., Sajomsang, W. and Opanasopit, P. 2019. Effects of silymarin-loaded amphiphilic chitosan polymeric micelles on the renal toxicity and anticancer activity of cisplatin. Pharmaceutical development and technology, 24(8): 927-934.

Tuli, H.S., Mittal, S., Aggarwal, D., Parashar, G., Parashar, N.C., Upadhyay, S.K., Barwal, T.S., Jain, A., Kaur, G. and Savla, R. 2020. Path of silibinin from diet to medicine: A dietary polyphenolic flavonoid having potential anti-cancer therapeutic significance. In: Seminars in Cancer Biology. Elsevier.

Won, D.-H., Kim, L.-H., Jang, B., Yang, I.-H., Kwon, H.-J., Jin, B., Oh, S.H., Kang, J.-H., Hong, S.-D. and Shin, J.-A. 2018. In vitro and in vivo anti-cancer activity of silymarin on oral cancer. Tumor Biology, 40(5): 1010428318776170.